Setlolo sa Semela

Setlolo sa Lekhasi la Mohloaare

● Setlolo sa lekhasi la mohlwaare ke motsoako oa tlhaho o sebetsang o tsoang makhasing a sefate sa mohlwaare (Olea europaea), o lengoang haholo-holo sebakeng sa Mediterranean. Setlolo sa lekhasi la mohlwaare ke motsoako oa tlhaho o feto-fetohang o nang le melemo ea ho loantša likokoana-hloko, ho loantša li-antioxidant le metabolism e loketseng ba nang le khatello e phahameng ea mali, sesole sa 'mele se fokolang, kapa litlhoko tsa ho thibela botsofali.

Lebitso la Sehlahisoa: Setlolo sa Lekhasi la Mohloaare (Setlolo sa Lekhasi la Olea europaea)

Lebitso la Selatine: Olea europaea L.

Lisebelisoa tse Sebetsang: Oleuropein, Hydroxytyrosol, Flavonoids

Litlhaloso: Oleuropein 10%-80% (e ka fetoloa)

Iteanye le rona

lintlha tsa sehlahisoa

Tlhaloso ea Sehlahisoa

tlhaloso1

tlhaloso2

Tlhahisoleseding ea Motheo

Lebitso la Sehlahisoa: Setlolo sa Lekhasi la Mohloaare (Setlolo sa Lekhasi la Olea europaea)

Lebitso la Selatine:Olea europaea L.

Lisebelisoa tse Sebetsang: Oleuropein, Hydroxytyrosol, Flavonoids

Litlhaloso: Oleuropein 10%-80% (e ka fetoloa)

Ponahalo: Phofo e ntle e sootho ho isa ho e tšoeu

Tlhaloso

Lisebelisoa	E tloaelehileng
Oleuropein [32619-42-4]	10%-80% ka HPLC
Hydroxytyrosol [10597-60-1]	10%-98% ka HPLC
Li-flavonoid	10-60% ka UV

Melemo ea Sehlahisoa

index_10-7 — Bohloeki bo Phahameng

Ho ntša oli e tsoetseng pele ho netefatsa hore Oleuropein e na le ≥80% bakeng sa katleho e phahameng ka ho fetisisa.

Melemo

Tšireletso ea 'mele ea ho itšireletsa mafung

● E eketsa ts'ebetso ea lisele tsa NK ka 37% (J Ethnopharmacol. 2020)

● E thibela kokoana-hloko ea ntaramane neuraminidase (IC50=0.78 μg/mL)

Taolo ea Tsoekere ea Mali

● E eketsa kutloisiso ea insulin ka ho kenya tšebetsong AMPK (e fokotsa HbA1c ka 1.2%)

● E thibela α-glucosidase (IC50=45.2 μg/mL) ho diehisa ho monngoa ha lik'habohaedreite.

Tšireletso ea Pelo le Methapo ea Methapo

● Hydroxytyrosol e fokotsa ho thehwa ha ox-LDL (-29%) mme e ntlafatsa tshebetso ya endothelial.

● Ho bontšitsoe ka bongaka hore khatello ea mali ea systolic e tlase ka 6.4 mmHg (teko ea libeke tse 8)

Bophelo bo Botle ba Letlalo

● E thibela mosebetsi oa MMP-1 ka 62% ho thibela ho senyeha ha collagen e bakoang ke UV

● MIC khahlanong le C. acnes: 0.05%

Likopo Boholo bo botala

Meriana le Nutraceuticals
• Adjuvant ea antiviral (e sebetsang khahlanong le EBV, HSV-1, jj.)
• Motsoako oa bohlokoa bakeng sa mekhoa ea metabolic syndrome

Lijo tse sebetsang
• Lino tse tšehetsang tsoekere maling (tse sebelisanang le chromium)
• Dikhasepolise tsa antioxidant (tse ntlafaditsweng ka astaxanthin)

Tlhokomelo ea Motho ka Mong
• Li-serum tsa kalafo ea makhopho (khakanyo ea 0.5-1%)
• Li-cream tse thibelang botsofali (li thibela ho thehoa ha AGEs)

Tekanyo e Khothaletsoang

● Sejo se eketsang lijo: 50-200mg/letsatsi (motheong oa oleuropein)

● Tšebeliso ea ka ntle ho letlalo: Ho tsepamisa mohopolo ho sireletsehileng ka 1-3%

Mehato ya tlhokomelo

※ Buisana le mofani oa tlhokomelo ea bophelo nakong ea boimana

※ Lekola khatello ea mali ha e kopantsoe le meriana e fokotsang khatello ea mali

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